Based on the robust preclinical and clinical data surrounding the important role of renal sympathetic nerves in various aspects of blood pressure control1, a novel catheter-based approach using radiofrequency energy to target and disrupt the renal nerves selectively has been developed2. Available evidence from trials in patients with resistant hypertension in whom renal denervation has been performed indicate that the procedure has a favourable safety profile2 and is associated with a substantial and sustained blood pressure reduction3.
In this issue of the journal, Lenski and colleagues noted that antihypertensive treatment with renal denervation was accompanied by a significant improvement ...
Neurovascular Hypertension & Kidney Disease and Human Neurotransmitters Laboratories, Baker IDI Heart & Diabetes Institute and Faculty of Medicine, Nursing & Health Sciences, Monash University, Melbourne, Victoria, Australia
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