Coronary interventions

Changes in post-PCI optimisation strategies with post-procedural FFR followed by IVUS

EuroIntervention 2023;19:80-82. DOI: 10.4244/EIJ-D-22-00755

Tara Neleman
Tara Neleman1, BSc; Frederik T. W. Groenland1, MD; Annemieke C. Ziedses des Plantes1, BSc; Alessandra Scoccia1, MD; Laurens J.C. van Zandvoort1, PhD; Eric Boersma1, PhD; Rutger-Jan Nuis1, MD, PhD; Wijnand K. den Dekker1, MD, PhD; Roberto Diletti1, MD, PhD; Jeroen Wilschut1, MD; Felix Zijlstra1, MD, PhD; Nicolas M. Van Mieghem1, MD, PhD; Joost Daemen1, MD, PhD
1. Department of Cardiology, Thorax Center, Erasmus University Medical Center, Rotterdam, the Netherlands
Suboptimal post-percutaneous coronary intervention (PCI) fractional flow reserve (FFR) values have been related to target vessel failure1. In the randomised FFR REACT trial, intravascular ultrasound (IVUS)-guided PCI optimisation in patients with a post-PCI FFR <0.90 significantly improved post-PCI FFR values2. The aim of this prespecified subanalysis was to assess the impact of post-PCI IVUS findings in addition to FFR pullback data on operator-defined optimisation strategies, assessed through a dedicated questionnaire.

The rationale and design of the FFR REACT trial have been published previously2. In brief, patients with an angiographically successful PCI and a post-PCI FFR &...

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