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Updating the evidence on patent foramen ovale closure versus medical therapy in patients with cryptogenic stroke: a systematic review and comprehensive meta-analysis of 2,303 patients from three randomised trials and 2,231 patients from 11 observational studies

EuroIntervention 2014;9:1342-1349 published online ahead of print July 2013. DOI: 10.4244/EIJV9I11A225

1. Ferrarotto Hospital, University of Catania, Catania, Italy; 2. ETNA Foundation, Catania, Italy

Aims: We aimed at updating the evidence coming from randomised and observational studies of patent foramen ovale (PFO) closure compared to medic

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