Renal denervation by CT-guided periarterial injection of hyperosmolar saline, vincristine, paclitaxel and guanethidine in a pig model

EuroIntervention 2017;12:e2262-e2270 published online November 2016 published online e-edition April 2017. DOI: 10.4244/EIJ-D-15-00354

Patrick Freyhardt
Patrick Freyhardt1*, MD; Ricardo Donners1, MD; Alex Riemert1, DVM; Jörg Schnorr1, DVM; Nicola Stolzenburg1, DVM; Jan L. Rinnenthal2, MD; Ulrich Bernhardt3, PhD; Bernd Hamm1, MD; Rolf W. Günther1, MD; Florian Streitparth1, MD
1. Department of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany; 2. Department of Neuropathology, Charité Universitätsmedizin Berlin, Berlin, Germany; 3. InnoRa GmbH, Berlin, Germany

Aims: The aim of the study was to evaluate the feasibility, safety and efficacy of renal sympathetic denervation with CT-guided periarterial injection of potentially neurolytic agents in

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arterial hypertensionguanethidinepaclitaxelrenal denervationrenal sympathicolysisvincristine
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