Randomised, blinded and controlled comparative study of chemical and radiofrequency-based renal denervation in a porcine model

EuroIntervention 2017;12:e1898-e1906 published online November 2016 published online e-edition February 2017. DOI: 10.4244/EIJ-D-16-00206

Stefan Bertog
Stefan Bertog1*, MD; Tim A. Fischell2, MD; Félix Vega3, VMD; Vartan Ghazarossian3, PhD; Atul Pathak4, MD, PhD; Laura Vaskelyte1, MD; Darrin Kent5, BS; Horst Sievert1, MD; Elena Ladich6, MD; Kazuyuki Yahagi6, MD; Renu Virmani6, MD
1. CardioVascular Center Frankfurt, Frankfurt, Germany; 2. Borgess Heart Institute, Kalamazoo, MI, USA; 3. Ablative Solutions, Inc., Palo Alto, CA, USA; 4. University Hospital, Toulouse, France; 5. Rev.1 Engineering LLC, Murrieta, CA, USA; 6. CVPath Insti

Aims: The blood pressure-lowering effect of percutaneous renal denervation (RDN) is controversial. The success of RDN may be device-dependent. We sought to compare the efficacy of RDN by

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chemical neurolysisnerve injurynorepinephrine concentrationradiofrequency denervationrenal denervation
Interventions for hypertensionRenal denervationTools, devices and techniques
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