IMAGE IN CARDIOLOGY

DOI: 10.4244/EIJV12I7A142

Plaque protrusion compromising bioresorbable coronary scaffold patency

Vincent Floré1*, MD, PhD; Mariano Pellicano1, MD; Julien Adjedj1, MD; Angela Ferrara1, MD; Kris Van Der Steen2, MD; Jozef Bartunek1, MD, PhD

The patient was a 53-year-old (male) suffering from unstable angina due to stenosis of the left anterior descending (LAD) artery. After 2.5 mm balloon predilatation (12 atm), a 3.0×28 mm bioresorbable vascular scaffold (BVS) (Absorb™; Abbott Vascular, Santa Clara, CA, USA) was implanted at 14 atm with an angiographically good result (Panel A). The patient was discharged on aspirin and clopidogrel.

Coronary angiography one month later showed a severe lesion in the distal part of the BVS, suggesting in-stent thrombosis (Panel B). Optical coherence tomography (OCT) confirmed mixed thrombus (Panel C, Panel D). With an aspiration catheter, a white structure measuring 9×2 mm (Panel F) was evacuated. Control OCT confirmed the disappearance of a protrusive structure, revealing an area of suboptimal BVS expansion and apposition (Panel E). A 3.5 mm non-compliant balloon post-dilatation (16 atm) was performed. OCT re-evaluation after one month was inconspicuous.

Platelet reactivity test (Multiplate® analyser; Roche Diagnostics Limited, Rotkreuz, Switzerland) demonstrated normal response to clopidogrel. Histologic examination of the aspirated debris revealed atherosclerotic plaque with a high concentration of cholesterol crystals, histiocytes, lymphocytes and red blood cells (Panel G, Panel H).

Although suggestive of in-scaffold thrombosis, this image shows the probable cause to be plaque protrusion into the scaffold lumen. The mechanism is eccentric plaque position in combination with insufficient expansion and apposition of a BVS within an angulated segment. This case emphasises the need for lesion preparation and post-implant optimisation when implanting BVS.

Conflict of interest statement

The authors have no conflicts of interest to declare.

Volume 12 Number 7
Sep 18, 2016
Volume 12 Number 7
View full issue


Key metrics

Suggested by Cory

EXPERT REVIEW

10.4244/EIJ-D-16-00471 Feb 20, 2017
Possible mechanical causes of scaffold thrombosis: insights from case reports with intracoronary imaging
Sotomi Y et al
free

IMAGE IN CARDIOLOGY

10.4244/EIJY14M10_07 Nov 20, 2015
Subacute thrombosis of a bioresorbable vascular scaffold implanted for recurrent in-stent restenosis
Rivero F et al
free

SHORT REPORT

10.4244/EIJ-D-17-00353 Apr 6, 2018
Very late scaffold thrombosis: insights from optical coherence tomography and histopathology
Joner M et al
free

IMAGE IN CARDIOLOGY

10.4244/EIJV10I5A103 Sep 28, 2014
Acute Absorb bioresorbable vascular scaffold thrombosis in ST-segment elevation myocardial infarction: to stent or not to stent?
Fernández-Rodríguez D et al
free

IMAGE IN CARDIOLOGY

10.4244/EIJ-D-16-00259 Mar 20, 2017
Neoatherosclerosis: an emerging and conceptually unexpected cause of very late bioresorbable vascular scaffold failure
Hiltrop N et al
free

IMAGE IN CARDIOLOGY

10.4244/EIJV12I1A10 May 16, 2016
Coronary aneurysm without malapposition after bioresorbable vascular scaffold implantation
Timmers L et al
free
Trending articles
151.43

State-of-the-Art

10.4244/EIJ-D-22-00776 Apr 3, 2023
Computed tomographic angiography in coronary artery disease
Serruys PW et al
free
55.9

Clinical research

10.4244/EIJ-D-22-00621 Feb 20, 2023
Long-term changes in coronary physiology after aortic valve replacement
Sabbah M et al
free
54.9

Expert review

10.4244/EIJ-D-21-01010 Jun 24, 2022
Device-related thrombus following left atrial appendage occlusion
Simard T et al
free
43.75

Clinical Research

10.4244/EIJ-D-21-01091 Aug 5, 2022
Lifetime management of patients with symptomatic severe aortic stenosis: a computed tomography simulation study
Medranda G et al
free
39.95

Clinical research

10.4244/EIJ-D-22-00558 Feb 6, 2023
Permanent pacemaker implantation and left bundle branch block with self-expanding valves – a SCOPE 2 subanalysis
Pellegrini C et al
free
X

The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

EuroPCR EAPCI
PCR ESC
Impact factor: 7.6
2023 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2024)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2024 Europa Group - All rights reserved