The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Interventions for valvular disease and heart failure

Clinical experience with a novel large bore vascular closure device after transfemoral transcatheter aortic valve replacement

EuroIntervention 2020;16:262-265. DOI: 10.4244/EIJ-D-19-00523

1. Department of Cardiovascular Surgery, INSURE (Institute for Translational Cardiac Surgery), German Heart Center, TUM, Munich, Germany; 2. Department of Cardiovascular Surgery, German Heart Center Munich, TUM, Munich, Germany; 3. Department of Anaesthesiology, German Heart Center Munich, TUM, Munich, Germany; 4. Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, Bad Oeynhausen, Germany


Utilisation of transcatheter aortic valve replacement (TAVR) is increasing. Vascular complications after transfemoral TAVR are still of concern. The majority are related to the large bore puncture site1. Currently, large bore arteriotomy closure relies on suture-based techniques, such as the Perclose ProGlide® or Prostar® XL devices (Abbott Vascular, Santa Clara, CA, USA). Closure devices such as MANTA® (Teleflex, Wayne, PA, USA) or PerQSeal® (Vivasure Medical, Galway, Ireland) are designed to seal large bore arteriotomies and have recently become available. The novel InClosure® vascular closure device (VCD) (InSeal Medical, Caesarea, Israel) provides haemostasis ...

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