Chordal replacement and annuloplasty in one transfemoral device for degenerative mitral regurgitation

DOI: 10.4244/EIJ-D-22-00345

Peter Skarsgard
Peter Skarsgard1,2, MD, FRCSC; Christopher Durkin3, MD, FRCPC; Jacqueline Saw4, MD, FSCAI, FACC, FAHA, FRCPC, FSCCT
1. Division of Cardiovascular Surgery, Vancouver General Hospital and the University of British Columbia, Vancouver, Canada; 2. Vesalius Cardiovascular Inc., Vancouver, Canada; 3. Division of Cardiac Anesthesia, Vancouver General Hospital and the University of British Columbia, Vancouver, Canada; 4. Division of Interventional Cardiology, Vancouver General Hospital and the University of British Columbia, Vancouver, Canada


Figure 1. The Vesalius transfemoral repair device. A) Device components: 1. annuloplasty ring, 2. leaflet net, 3. multisegment neochords, and 4. adjustment arches. B) The implanted device corrects anterior leaflet prolapse and MR.

Surgical mitral valve repair for degenerative mitral regurgitation (DMR) is effective for all prolapse complexities with or without annular dilation, a goal not yet achievable with existing transfemoral solutions.

A transfemoral mitral repair device that provides both chordal replacement (for leaflet prolapse) and annuloplasty (for annular dilation) could challenge the dominance of surgical repair. If the concept is feasible for all valve segments, then for such a device the ...

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