The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Part III – Ploughing new ground, update of the bioabsorbable programmes

A.R.T.: concept of a bioresorbable stent without drug elution

EuroIntervention Supplement (2009) Vol. 5 (Supplement F) F83-F87.

1. INSERM U970, Paris, France; 2. Cardiology department, HEGP, APHP, Paris, France; 3. University Paris-Descartes, Paris, France
Why bioresorbable stents?

More than 20 years ago, interventional cardiology was launched by Andreas Grüntzig, introducing a revolutionary innovation, i.e., percutaneous balloon angioplasty1. The 316L stainless steel stent was initially introduced to tackle acute closure secondary to dissections following balloon angioplasty. In fact, the stent not only resolved the acute complications, but also appeared to be the appropriate response to the midterm complication, i.e., restenosis2,3. Indeed, the principal mechanism of restenosis after balloon angioplasty appeared to be related to chronic constrictive remodelling as a negative component of the healing process4-6. Nevertheless, the permanent (316L stainless steel) ...

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