Image – Interventional flashlight

DOI: 10.4244/EIJ-D-19-00058

AMPLATZER Muscular Ventricular Septal Occluder in transcatheter occlusion of the left main coronary artery in a patient with a huge aneurysm secondary to Kawasaki disease

Ferit Onur Mutluer1, MD; Ömer Yildiz1, MD; Alpay Çeliker2, MD

Figure 1. Fluoroscopic images. A) Coronary angiogram showing the aneurysm (a) and dissection (d). B) Aortogram showing the device (*) deployed.

Chronic coronary aneurysms are present in 6% of patients with Kawasaki disease (KD) and are associated with long-term morbidity and mortality1,2. There are several interventional treatment options for coronary aneurysms3. Herein we report the first successful use of transcatheter occlusion of a huge left main coronary artery (LMCA) aneurysm due to KD with an AMPLATZER™ Muscular Ventricular Septal Occluder device (VSO; St. Jude Medical, St. Paul, MN, USA).

The 16-year-old male patient with previous history of KD and coronary artery bypass grafting presented with exercise-induced ventricular tachycardia (VT). Baseline echocardiogram (ECG) and laboratory tests were unremarkable. The coronary angiogram showed a 4 cm diameter left main coronary artery (LMCA) aneurysm, patent grafts to the left anterior descending (LAD) and left circumflex (LCX) arteries and dissection in the posterolateral (PL) branch of the LCX (Figure 1A, Moving image 1). Following implantable cardioverter defibrillator (ICD) implantation, transcatheter closure of the LMCA was planned. After right femoral artery access and administration of 100 IU/kg of unfractionated heparin, two hydrophilic coronary guidewires were positioned in the LCX and the delivery catheter was positioned in the LMCA. A 6 mm AMPLATZER Muscular VSO was advanced into the aneurysm. The first disc was deployed in the isthmus of the aneurysm and the second disc was deployed in the aortic side of the LMCA ostium. The patient was observed for 15 minutes before release of the device (Figure 1B, Moving image 2, Moving image 3). The ostia of the LAD and LCX were not affected, as shown by non-selective visualisation during aortography. Clopidogrel was discontinued following dual antiplatelet therapy for 12 months.

We demonstrated that transcatheter occlusion of ostial coronary aneurysms with occlusion devices is a safe and efficient method for protecting patients from complications in the long run.

Conflict of interest statement

The authors have no conflicts of interest to declare.

Supplementary data

To read the full content of this article, please download the PDF.

Moving image 1. Coronary angiogram showing the aneurysm and the dissection.

Moving image 2. Aortogram before the device was released.

Moving image 3. Aortogram after the release of the device, small through-device leak.

Volume 15 Number 7
Sep 20, 2019
Volume 15 Number 7
View full issue


Key metrics

Suggested by Cory

10.4244/EIJV9I11A228 Mar 20, 2014
How should I treat a coronary bifurcation wide-neck aneurysm?
Sgueglia G et al
free

10.4244/EIJV11I7A171 Nov 20, 2015
How should I treat multiple coronary aneurysms with severe stenoses?
Warisawa T et al
free

IMAGE IN CARDIOLOGY

10.4244/EIJV12I9A190 Oct 20, 2016
An unexpected huge coronary aneurysm
Chan Y et al
free

IMAGE IN CARDIOLOGY

10.4244/EIJV11I6A132 Oct 20, 2015
A curly case: dissecting giant arteriovenous anomaly - left main coronary artery shunting to superior vena cava
de Mulder M et al
free

Image – Interventional flashlight

10.4244/EIJ-D-19-00214 Mar 20, 2020
Left main bifurcation PCI with the culotte technique using two self-apposing stents
Scotti A et al
free

IMAGE IN CARDIOLOGY

10.4244/EIJV12I1A11 May 16, 2016
Embolic myocardial infarction due to coronary artery aneurysm in a patient with Loeys-Dietz syndrome
Cereda A et al
free
Trending articles
318.1

State-of-the-Art Review

10.4244/EIJ-D-21-00695 Nov 19, 2021
Transcatheter treatment for tricuspid valve disease
Praz F et al
free
116.75

State-of-the-Art

10.4244/EIJ-D-24-00066 Apr 21, 2025
Management of complications after valvular interventions
Bansal A et al
free
108.3

Viewpoint

10.4244/EIJ-E-22-00007 May 15, 2022
TAVI at 20: how a crazy idea led to a clinical revolution
Eltchaninoff H et al
free
91.6

Image – Interventional flashlight

10.4244/EIJ-D-22-00344 Aug 5, 2022
First dedicated transcatheter leaflet splitting device: the ShortCut device
Tchétché D et al
free
72.4

State-of-the-art

10.4244/EIJ-D-22-00627 Feb 6, 2023
Left atrial appendage occlusion
Holmes D et al
free
68.9

State-of-the-Art

10.4244/EIJ-D-24-00992 Sep 15, 2025
Antithrombotic therapy in complex percutaneous coronary intervention
Castiello D et al
free
60.65

Clinical research

10.4244/EIJ-D-20-01155 Oct 20, 2021
A deep learning algorithm for detecting acute myocardial infarction
Liu W et al
free
49.55

CLINICAL RESEARCH

10.4244/EIJ-D-17-00962 Apr 6, 2018
A new optical coherence tomography-based calcium scoring system to predict stent underexpansion
Fujino A et al
free
43.45

State-of-the-Art Review

10.4244/EIJ-D-21-00145 Sep 20, 2021
Robotics, imaging, and artificial intelligence in the catheterisation laboratory
Beyar R et al
free
X

PCR
Impact factor: 9.5
2024 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2025)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2025 Europa Group - All rights reserved