Technical report

A novel dedicated 3-dimensional quantitative coronary analysis methodology for bifurcation lesions

EuroIntervention 2011;7:629-635 publish online ahead of print January 2011. DOI: 10.4244/EIJV7I5A100

Yoshinobu Onuma
Yoshinobu Onuma1, MD; Chrysafios Girasis1, MD; Jean-Paul Aben2, BSC; Giovanna Sarno1, MD, PhD; Nicolo Piazza1, MD; Coen Lokkerbol2, BSc; Marie-Angel Morel3, Bsc; Patrick W. Serruys1*, MD PhD
1. Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands; 2. Pie Medical Imaging B.V., Maastricht, The Netherlands; 3. Cardialysis B.V., Rotterdam, The Netherlands

We developed a novel and dedicated three-dimensional (3-D) quantitative coronary analysis (QCA) software (Cardiovascular Angio-graphy Analysis System, Pie Medical Imaging, Maastricht, The Netherlands) to overcome potential limitations associated with two-dimensional (2-D) quantitative coronary analysis of bifurcation lesions (vessel overlap, foreshortening).

By combining two 2-D image data sets, the new CAAS 5, QCA 3-D bifurcation software is able to perform a 3-D reconstruction of the bifurcation and determine lesion characteristics including bifurcation angle. This is achieved in the following steps: i) Contour detection on two angiographic projections of the involved vessel segments including the bifurcation segment identification of a ...

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