The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)


Strengths and weaknesses of different types of TAVI study

EuroIntervention 2020;15:e1301-e1304. DOI: 10.4244/EIJV15I15A236

1. The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

During the past decade, several important clinical trials have provided evidence supporting a paradigm shift from surgical aortic valve replacement (SAVR) towards transcatheter aortic valve implantation (TAVI) for the treatment of patients with symptomatic severe aortic valve stenosis (AS). Randomised controlled trials (RCTs) are the cornerstone of evidence-based medicine and have been the major driver of this paradigm shift. However, other study types such as international multicentre registries (both prospective and retrospective), post-market real-world surveillance studies, and head-to-head comparisons of different types of transcatheter heart valve (THV) are also needed in order to strengthen this evidence and provide insights ...

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