The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Editorial

OCT-derived coronary calcified nodules as a predictor of high-risk patients

EuroIntervention 2020;16:361-363. DOI: 10.4244/EIJV16I5A65

1. Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan


Vascular calcification is one of the important components of arteriosclerosis. Calcification is frequently observed in coronary arteries with advanced arteriosclerosis. Intravascular optical coherence tomography (OCT) can clearly visualise coronary calcification in vivo. OCT images of coronary calcification are characterised by well-delineated, signal-poor regions with sharp borders. Coronary calcifications are morphologically classified as calcium sheet or nodule. Nodular calcifications protruding into the coronary lumen (called calcified nodules) are found in the culprit lesion of acute coronary syndrome1. Furthermore, such protruding nodular calcifications are also identified in non-culprit lesions. A limited number of studies have evaluated the pathophysiology of calcified nodules.##...

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