Coronary sinus to mitral valve annulus topography and response to the percutaneous coronary sinus-based mitral valve contour system

Introduction

The Carillon® Mitral Contour System® (Cardiac Dimensions, Kirkland, WA, USA) for coronary sinus (CS)-based percutaneous mitral valve repair has demonstrated a reduction in functional mitral valve regurgitation (FMR) in heart failure patients1,2. However, an acute reduction in FMR determined by echocardiography cannot be achieved in all patients: the AMADEUS trial reported that there was no acute effect on FMR in 18.6% of the patients2. However, three-dimensional (3D) imaging modalities for percutaneous valve interventions have been implemented in clinical routine. For example, multislice computed tomography (MSCT) is pivotal for procedural planning of transcatheter aortic valve implantation (...