Original Research

DOI: 10.4244/EIJ-D-23-00512

Clinical characteristics and outcomes of patients requiring prolonged mechanical circulatory support after high-risk percutaneous coronary intervention

Sugi Min1, MD; Mir Babar Basir2, DO; Alejandro Lemor3, MD, MS; Zhipeng Zhou4, MA; Arsalan Abu-Much4, MD; Björn Redfors4,5,6, MD, PhD; Julia B. Thompson4, MS; Alexander G. Truesdell7,8, MD; Aditya S. Bharadwaj9, MD; Yanru Li4, MPH, MS; Amir Kaki10, MD; Brigitta C. Brott11, MD; David H. Wohns12, MD; Perwaiz M. Meraj13, MD; Ramesh Daggubati14, MD; Cindy L. Grines15,16, MD; William W. O'Neill17, MD; Jeffrey W. Moses1,18, MD

Abstract

BACKGROUND: There are limited data on the clinical characteristics and outcomes of patients who require prolonged mechanical circulatory support (MCS) after Impella-supported high-risk percutaneous coronary intervention (HR-PCI).

AIMS: The aim of this study is to describe the contemporary clinical characteristics, outcomes, and predictors associated with prolonged MCS support after assisted HR-PCI.

METHODS: Patients enrolled in the prospective, multicentre, clinical endpoint-adjudicated PROTECT III study who had undergone HR-PCI using Impella were evaluated. Patient and procedural characteristics and outcomes for those who received prolonged MCS beyond the duration of their index procedure were compared to those in whom MCS was successfully weaned and explanted at the conclusion of the index PCI.

RESULTS: Among 1,155 patients who underwent HR-PCI with Impella between 2017 and 2020 and had sufficient data to confirm the duration of Impella support, 16.5% received prolonged MCS (mean duration 25.2±31.1 hours compared with 1.8±5.8 hours for those who only received intraprocedural MCS). Patients receiving prolonged support presented with more urgent indications (e.g., acute coronary syndromes [ACS], lower ejection fraction [EF], elevated baseline heart rate and lower systolic blood pressure)....

Sign in to read
the full article

Forgot your password?
No account yet?
Sign up for free!

Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com

Volume 20 Number 2
Jan 15, 2024
Volume 20 Number 2
View full issue


Key metrics

On the same subject

Clinical research

10.4244/EIJ-D-18-01126 Aug 29, 2019
New-generation mechanical circulatory support during high-risk PCI: a cross-sectional analysis
Ameloot K et al
free

Editorial

10.4244/EIJ-E-23-00053 Jan 15, 2024
High-risk PCI: one device cannot fix it all
Chieffo A and Iannaccone M
free

10.4244/EIJ-D-19-00279L Oct 18, 2019
Impella device use in high-risk PCI
Chhabra L et al
free

10.4244/EIJV13I18A344 Apr 6, 2018
Mechanical circulatory support: the last resort in cardiogenic shock?
Thiele H et al
free

Expert review

10.4244/EIJY21M05_01 Jul 20, 2021
Joint EAPCI/ACVC expert consensus document on percutaneous ventricular assist devices
Chieffo A et al
free
Trending articles
188.3

State-of-the-Art Review

10.4244/EIJ-D-21-01034 Jun 3, 2022
Management of in-stent restenosis
Alfonso F et al
free
170.15

Translational research

10.4244/EIJ-D-21-00824 May 15, 2022
Bench test and in vivo evaluation of longitudinal stent deformation during proximal optimisation
Toth GG et al
free
159.45

Expert review

10.4244/EIJ-D-21-00690 May 15, 2022
Crush techniques for percutaneous coronary intervention of bifurcation lesions
Moroni F et al
free
133.08

State-of-the-Art

10.4244/EIJ-D-22-00776 Apr 3, 2023
Computed tomographic angiography in coronary artery disease
Serruys PW et al
free
108.75

Viewpoint

10.4244/EIJ-E-22-00007 May 15, 2022
TAVI at 20: how a crazy idea led to a clinical revolution
Eltchaninoff H et al
free
X

The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

EuroPCR EAPCI
PCR ESC
Impact factor: 6.2
2022 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2023)
Online ISSN 1969-6213 - Print ISSN 1774-024X
© 2005-2024 Europa Group - All rights reserved