2. Aix Marseille Univ, IFSTTAR, LBA, Marseille, France
3. Aix Marseille Univ, IFSTTAR, LBA, Marseille, France
4. Aix Marseille Univ, IFSTTAR, LBA, Marseille, France
5. Polyclinique Les Fleurs, Ollioules, France
6. Aix Marseille Univ, IFSTTAR, LBA, Marseille, France
7. Aix Marseille Univ, IFSTTAR, LBA, Marseille, France
8. Quebec Heart and Lung Institute, Laval University, Quebec, Canada
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Methods and results: For in-vitro testing, a double activation simulator was used, with a biological valve mounted in aortic position. A non-contact system based on stereophotogammetry and digital image correlation (DIC) with high spatial and temporal resolution (2000img/sec) enabled to film and study frame-by-frame the valve’s leaflet movement and perform the three-dimensional analysis. Secondly, a finite element model of the valve was developed. Finally, the deformation obtained from the DIC analysis was applied in the finite element model which allows a realistic opening and closing of each leaflet, in order to calculate the local mechanical stress applied. High stress regions were primarily observed in the upper leaflet edge and belly and to a lesser extent at the free leaflet edge. The maximum principal stress on leaflet reached to 1.97 MPa.
Conclusions:This coupled in-vitro/in-silico method offers a new experimental evaluation of the mechanical stress applied on bioprosthesis leaflets during in-vitro mechanical conditioning, which is important for better understanding of the valve durability.
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