Arterial hypertension is among the leading global risks for mortality, being responsible for 9.4 million deaths in 2010.
The reason for this enormous burden has been documented in multiple studies. Hypertension is strongly associated with overall cardiovascular risk. Increased blood pressure contributes to cardiovascular and cerebrovascular endpoints, such as myocardial infarction, heart failure, cardiovascular death and stroke. In addition, an age-dependent positive correlation exists between systolic blood pressure (SBP)/ diastolic blood pressure (DBP) and stroke, as well as between SBP/DBP and ischaemic heart disease. All these data suggest that hypertension is the number one risk for mortality because ...
Charité-Universitaetsmedizin Berlin, Center for Cardiovascular Research, CCR Institute of Pharmacology, Berlin, Germany
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