Assessment of the microcirculation of the heart has gained interest over recent years. This is partly due to the fact that up to 50% of patients with chest pain visiting the catheterisation laboratory do not present with significant epicardial stenosis (so-called angina with non-obstructive coronary artery disease [ANOCA])1.
Most knowledge regarding microvascular resistance has come from non-invasive imaging, from invasive index of microvascular resistance2, or from Doppler wires3, all of which are semi-quantitative and operator-dependent.
Recently, direct quantitative measurement of coronary blood flow and microvascular resistance has become possible by thermodilution with saline infusion, using a pressure-temperature ...
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