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Paclitaxel-eluting stent restenosis shows three-layer appearance by optical coherence tomography


Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
A 73-year-old woman with hypertension, hyperlipidemia and positive familial history of coronary artery disease presented with Canadian Cardiovascular Society class III angina and underwent coronary angiography, which showed a chronic occluded right coronary artery (Panel A). The vessel was recanalized and treated with three paclitaxel-eluting stents (TAXUS®, Boston Scientific: 3.5 x 32 mm distally, 3.5 x 28 mm in the middle part, 3.5 x 12 mm proximally). Postintervention coronary angiography showed a good result (Panel B). Twelve-month follow-up angiography revealed focal in-stent restenosis (Panel C). Intracoronary optical coherence tomography (OCT: LightLabImaging™, Boston, MA, USA) pullback displayed well-expanded stents covered with a thin, homogenous, highly reflective neointimal ...

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