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Impact of single or multicentre study design on the results of trials examining the efficacy of adjunctive devices to prevent distal embolisation during acute myocardial infarction

EuroIntervention 2009;5:375-383 - DOI10.4244/EIJV5I3A59.

Y Inaba
Yoichi Inaba1*, MD; Jennifer A. Chen2, MD; Nisha Mehta2, MD; Steven R. Bergmann3, MD, PhD
1. Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR, USA; 2. Division of Medicine, Beth Israel Medical Center, New York, NY, USA; 3. Division of Cardiology, Beth Israel Medical Center, New York, NY, USA

Aims: We investigated using meta-analytic techniques, whether, and to what degree, single or multicentre study design affects clinical outcomes in randomised controlled trials examining the

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