The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

Image in cardiology

A unique feature of thin flat thrombus visualised by optical coherence tomography

EuroIntervention 2013;9:1008. DOI: 10.4244/EIJV9I8A169

Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan

Sign in to read and download the full article

Forgot your password?
No account yet? Sign up for free!
Create my pcr account

Join us for free and access thousands of articles from EuroIntervention, as well as presentations, videos, cases from PCRonline.com

Optical coherence tomography (OCT) has recently been developed as a high-resolution intravascular imaging modality, detecting small abnormal structures in the coronary lumen that could not be visualised by intravascular ultrasound (IVUS).

A 77-year-old man died with acute myelogenous leukemia. After he died, the coronary artery was imaged by OCT (ImageWire; LightLab Imaging, Westford, MA, USA) and IVUS (Atlantis SR Pro, 40 MHz; Boston Scientific, Natick, MA, USA). OCT clearly demonstrated a thin flat structure in the coronary lumen (Figure 1A, Moving image 1) but not in the IVUS image. This unique structural feature was demonstrated in corresponding histological images (Figure 1B, arrowhead). It revealed a white thrombus consisting mainly of platelets and white blood cells (Figure 1C and Figure 1D). This thin flat white thrombus was attached to the vessel wall without significant lumen stenosis.

High-resolution OCT was able to detect a unique feature of thrombus such as a thin flat structure in the coronary lumen. The clinical impact of this abnormal structure is still unclear. However, differentiation of intimal dissection might be necessary in the clinical setting.

Figure 1. A thin flat thrombus visualised by optical coherence tomography. A thin flat structure in the coronary lumen was visualised by optical coherence tomography (A). Histological images revealed a white thrombus consisting mainly of platelets and white blood cells (B-D).

Conflict of interest statement

The authors have no conflicts of interest to declare.

Online data supplement

Moving image 1. OCT demonstrating a thin flat structure protruding into the coronary lumen during pullback.

Supplementary data

  • Moving image 1. OCT demonstrating a thin flat structure protruding into the coronary lumen during pullback.

Read next article

The coronary artery bypass graft SYNTAX Score: final five-year outcomes from the SYNTAX-LE MANS left main angiographic substudy