We read with interest the letter by Georgios Tzanis et al1 concerning our study “Coronary sinus Reducer implantation results in improved oxygen kinetics at cardiopulmonary exercise test in patients with refractory angina”2.
In brief, in our manuscript we presented, for the first time, data regarding cardiopulmonary exercise testing before and after Reducer implantation. Improvements in oxygen kinetics were shown by increased VO2 max (+11.3%, p=0.026), increased VO2 at anaerobic threshold (+9.1%, p=0.06), and increased effort tolerance of approximately 34% (68±28 W vs 81±49 W, p=0.05). These observations were associated with consistent improvements in Canadian Cardiovascular Society class.
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