Wai Kin Chi1,2, MBChB, MRCP; Tong Liu3, MD, PhD; Luis Nombela-Franco4, MD, PhD; Gary Tse1,2, MD, PhD, FESC, FACC, FRCP, FHRS
1. Department of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China; 2. Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China; 3. Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China; 4. Cardiology Department, Instituto Cardiovascular, Hospital Clínico San Carlos, IdISSC, Madrid, Spain
We read with great interest the excellent article entitled “Prognostic impact of non-culprit chronic total occlusions in infarct-related cardiogenic shock: results of the randomised IABP-SHOCK II trial” by Saad et al1. The authors conducted a retrospective analysis to show that chronic total occlusion (CTO) in a non-infarct-related coronary artery (non-IRA) was an independent predictor of one-year mortality and 30-day ventricular arrhythmias in patients with cardiogenic shock (CS) complicating acute myocardial infarction (AMI). These findings complement previous findings that non-IRA CTOs were also arrhythmogenic, which translated into higher all-cause mortality2,3,4.
Our group recently conducted a systematic review and ...