Objective
to assess the clinical outcomes of transcatheter mitral-valve repair (TMV) compared to guidelines recommended treatment (GRT) for mitral regurgitation
Study
multicentre randomised trial
Population
patients with moderate to severe mitral valve regurgitation and heart-failure
Endpoints
1) first or recurrent hospitalisation for heart failure or cardiovascular death during 24 months 2) first or recurrent hospitalisation for heart failure during 24 months
Conclusion
among patients with heart failure with moderate to severe mitral regurgitation transcatheter mitral-valve repair and optimal medication achieved significant better clinical outcomes (hospitalisation/death) during 24 months compared to optimal medical treatment alone
Anker et al. NEJM 2024; August 31 online