1. Drug-eluting and bare metal stents

Thin-strut, bioresorbable polymer-coated EES

EVOLVE II – 5 years
Objective
to report the 5-year clinical adverse event rate of the Synergy stent (thin-strut, bioresorbable polymer-coated everolimus-eluting stents) compared to Promus Element Plus stent
Study
multicentre, randomised, non-inferiority trial (margin 4.4%)
Population
patients with stable angina or non STEMI
Endpoints
5-year target lesion failure: cardiac death, MI or ischaemia driven TLR
Conclusion
Synergy stent implantation was non-inferior compared to Promus stent implantation with respect to 5-year major adverse event rate in patients with stable CAD or non STEMI patients
Kereiakes et al. Circulation Cardiovasc Interv. 2019;12:e008152
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

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2023 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2024)
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