9. Intravascular imaging-guided PCI

QCA versus IVUS to guide DES-implantation

GUIDE-DES
Objective
to assess whether quantitative coronary angiography (QCA) to guide PCI is an alternative strategy to IVUS.
Study
prospective, open-label, multicentre randomised non-inferiority trial (margin 3.5%)
Population
patients with chronic acute coronary syndrome
Endpoints
target lesion failure at 12 months as composite of cardiac death, MI, or ischaemia-driven target lesion revascularisation
Conclusion
the rate of target lesion failure was not different between, QCA or IVUS guidance of PCI
Lee et al. JAMA cardiol. 2024;Online March
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