1. Drug-eluting and bare metal stents

Polymer-based vs polymer-free stents in patients at high bleeding risk

ONYX ONE
Objective
to compare polymer-based zotarolimus-eluting stents with polymer-free biolimus-coated stents in patients at high bleeding risk
Study
prospective, multicentre, non-inferiority randomised trial
Population
patients undergoing PCI classified as being at high bleeding risk
Endpoints
composite of death from cardiac causes, myocardial infarction, or stent thrombosis at 1 year
Conclusion
among patients at high bleeding risk who received 1 month DAPT after PCI, use of polymer-based zotarolimus-eluting stents was noninferior to use of polymer-free drug-coated stents with regard to safety
Windecker et al. N Eng J Med. 2020;382:1208-18
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

EuroPCR EAPCI
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2022 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2023)
Online ISSN 1969-6213 - Print ISSN 1774-024X
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