Objective
to investigate the clinical outcome of PCI for chronic total occlusion and optimal medical treatment (OMT) as compared with optimal medical treatment alone in terms of symptomatic improvement in patients with stable angina
Study
prospective, multicentre, open-label randomised trial (2:1)
Population
patients with single and multivessel disease. Patients with M-VD received first treatment of any significant non-CTO lesion >4 weeks before randomisation
Endpoints
change in health status as assessed with SAQ between treatment groups from baseline to 12 months (SAQ = Seattle angina questionnaire)
Conclusion
PCI for CTO is associated with an improvement of health status compared to optimal medical treatment in patients with stable angina
Werner et al. Eur Heart J. 2018;39:2484-93