Objective
to report the 5 year clinical outcomes of an ultra thin cobalt-chromium biodegradable-polymer sirolimus-eluting stent (ORSIRO) compared to a thin-strut, durable-polymer everolimus-eluting stent (Xience prime)
Study
single blind, multicenter randomised non-inferiority trial (margin 3.5%)
Population
all-comers
Endpoints
target-vessel failure as cardiac death, MI and clinically indicated TLR at 5Â years
Conclusion
the 5 year target vessel failure rate is similar for ultra thin strut biodegradable SES and thin strut durable polymer EES for PCI among all-comers
Pilgrim et al. Lancet. 2018;392:737-46
