2. PCI for STEMI

Fractional flow guided MV-PCI in STEMI

COMPARE-ACUTE 3 years
Objective
to investigate the 3-year clinical outcome of FFR-guided complete revascularisation compared to culprit-only treatment in patients with STEMI and MV-disease
Study
multicentre, randomised (1:2) trial
Population
patients with STEMI and MV-disease undergoing primary PCI
Endpoints
composite of all-cause mortality, non-fatal MI, any revascularisation and cerebrovascular events (MACCE) at 3 years (this was a secondary endpoint)
Conclusion
FFR-guided complete revascularisation of patients with STEMI and MV-disease reduced the 3-year revascularisation rate compared to infarct related artery only treatment but did not reduce all-cause mortality and non-fatal re-myocardial infarction
Smits et al. EuroIntervention. 2020;16:225-32
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

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2023 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2024)
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