Objective
to compare the efficacy of the treatment of resistant hypertension with 1) Radiofrequency renal sympathetic denervation (RDN) of main renal arteries, 2) Radiofrequency RDN of main renal arteries, side branches and accessories and 3) Endovascular ultra sound-based RDN of main renal artery
Study
single-blind, single-centre 3 arm randomised trial
Population
patients with resistant hypertension
Endpoints
change in systolic day time ambulatory blood pressure at 3 months
Conclusion
ultrasound-based ablation seems superior to radiofrequency ablation of the main renal arteries only. The benefit of radiofrequency ablation of main renal artery and side branches requires more study
Fengler et al. Circulation. 2019;139:590-600
