7. Myocardial revascularisation strategy

DES versus CABG for left main disease

PRECOMBAT 10 years
Objective
to report the 10-year outcomes of PCI compared to CABG for the treatment of left main-CAD
Study
multicentre randomised trial
Population
patients with LM-stenosis (>50%) in candidates suitable for either PCI or CABG
Endpoints
MACE or cerebrovascular events: any cause death, MI, stroke or ischaemia- driven target vessel revascularisation at 10 years
Conclusion
there was no significant difference in the 10 year incidence of major adverse cardiac or cerebrovascular events between treatment with PCI or CABG. Note: underpowered study
Park et al. Circulation. 2020;141:1437-46
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