2. PCI for STEMI

Complete or Culprit-lesion only for acute MI in older patients

FIRE
Objective
to investigate whether complete revascularisation using coronary physiology is superior to culprit-only PCI in older patients with acute MI
Study
investigator-initiated, multicentre, randomised trial
Population
older patients ( ≥ 75 years), with STEMI or NSTEMI and MV disease
Endpoints
composite of death, MI, stroke or ischemia driven revascularisation within 1 year
Conclusion
physiology-guided complete revascularisation resulted in significant lower incidence of 1-year MACE compared to culprit-only PCI in older patients with acute myocardial infarction
Biscaglia et al. N. Engl. J. Med 2023:online August 26
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

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2022 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2023)
Online ISSN 1969-6213 - Print ISSN 1774-024X
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