Objective
to assess the incidence of bleeding after TAVI treated with anticoagulation with or without clopidogrel for 3 months
Study
multicentre, open-label, randomised trial
Population
patients with an established indication for long term oral anticoagulation undergoing TAVI
Endpoints
2 primary endpoints: all bleeding and non-procedure related bleeding during 12 months. Procedure related bleeding was BARC type 4 severe bleeding
Conclusion
the incidence of serious bleeding over a period of 1 year was lower with oral anticoagulation alone compared to anticoagulation with clopidogrel in patients undergoing TAVI with indication for oral anticoagulation
Nijhuis et al. N Eng J Med. 2020;382:1696-707
