12. Cardiogenic shock and cardiac arrest

Angiography after out-of-hospital cardiac arrest without ST-segment elevation

TOMAHAWK
Objective
to compare immediate versus delayed angiography in patients OHCA
Study
randomized, international, multicenter, open-label trial
Population
patients with successfully resuscitated OHCA of possible coronary origin to undergo either immediate coronary angiography or initial intensive care assessment with delayed angiography
Endpoints
the primary end point was death from any cause at 30 days. Secondary endpoints included a composite of death from any cause or severe neurologic deficit at 30 days
Conclusion
in patients with resuscitated OHCA without ST-segment elevation, immediate angiography provided no benefit over delayed or selective angiography with respect to the 30-day risk of death from any cause
Desch et al. N Engl J Med.2021;385:2544-2553
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