Objective
to compare QFR-guided PCI with angiography-guided PCI
Study
multicentre, blinded, randomised, sham-controlled trial
Population
patients with stable or unstable angina or patients who had a myocardial infarction (MI) at least 72 hours before screening, who had at least one lesion with a diameter stenosis of 50-90%
Endpoints
the primary endpoint was the 1-year rate of major adverse cardiac events, a composite of death from any cause, MI, or ischaemia-driven revascularisation
Conclusion
in patients undergoing PCI, a QFR-guided strategy of lesion selection improved 1-year clinical outcomes compared with standard angiography guidance
Xu et al. Lancet. 2021;398:2149-59
