13. Percutaneous intervention for structural heart disease

Amplatzer Amulet™ left atrial appendage occluder

AMULET IDE 3 years
Objective
to report the 3-year clinical outcomes of the Amplatzer Amulet left atrial appendage occluder vs. Watchman occluder in patients with non-valvular atrial fibrillation (NVAF)
Study
multicentre randomised trial
Population
paroxysmal, persistent, or permanent NVAF with high risk of stroke or systemic embolism (CHADS2 score ≥2 or CHA2DS2-VASc score ≥3)
Endpoints
composite ischemic stroke or systemic embolism at 3 years
Conclusion
left atrial appendage occlusion with Amulet or Watchman resulted in comparable clinical outcomes through 3 years
Lakkireddy et al. J.Am.Coll. Cardiol Interv 2023; 16:1902-1913
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

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2022 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2023)
Online ISSN 1969-6213 - Print ISSN 1774-024X
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