11. Antithrombotic therapies

3/6-month versus 12-month DAPT after coronary intervention using contemporary DES with ultrathin struts

HOST-IDEA
Objective
to compare whether 3/6-month DAPT was non-inferior to 12-month DAPT after implantation of DES with ultrathin struts and advanced polymer technology
Study
prospective, multicentre, open label, randomised clinical trial
Population
adults with ischaemic heart disease (CCS or NSTE-ACS) undergoing PCI with the Orsiro biodegradable polymer DES or Coroflex ISAR polymer free DES
Endpoints
net adverse clinical events: a composite of cardiac death, target vessel MI, clinically driven TLR, ST or BARC types 3 or 5 bleeding at 12 months
Conclusion
among patients undergoing PCI using third-generation DES, 3/6-month DAPT was non-inferior to 12-month DAPT for net adverse clinical events
Han et al Circulation. 2023
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The Official Journal of EuroPCR and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

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2023 Journal Citation Reports®
Science Edition (Clarivate Analytics, 2024)
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