The Official Journal of EuroPCR and the European Association of Percutaneous Coronary Interventions (EAPCI)

14.1 - Renal denervation

Different renal denervation devices and techniques: RADIOSOUND-HTN

Objective

to compare the efficacy of the treatment of resistant hypertension with 1) Radiofrequency renal sympathetic denervation (RDN) of main renal arteries, 2) Radiofrequency RDN of main renal arteries, side branches and accessories and 3) Endovascular ultra sound-based RDN of main renal artery

Study

single-blind, single-centre 3 arm randomised trial

Population

patients with resistant hypertension

Endpoints

change in systolic day time ambulatory blood pressure at 3 months

Conclusion

ultrasound-based ablation seems superior to radiofrequency ablation of the main renal arteries only. The benefit of radiofrequency ablation of main renal artery and side branches requires more study

Fengler et al. Circulation 2019;139:590-600

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